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HomoloGene:11356. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PLA2G12B,  H.sapiens
phospholipase A2, group XIIB
NP_115951.2
195 aa
PLA2G12B,  P.troglodytes
phospholipase A2, group XIIB
XP_521692.2
195 aa
PLA2G12B,  M.mulatta
phospholipase A2, group XIIB
XP_001104302.1
194 aa
PLA2G12B,  C.lupus
phospholipase A2, group XIIB
XP_005619062.1
194 aa
PLA2G12B,  B.taurus
phospholipase A2, group XIIB
XP_002698920.1
195 aa
Pla2g12b,  M.musculus
phospholipase A2, group XIIB
NP_076019.2
195 aa
Pla2g12b,  R.norvegicus
phospholipase A2, group XIIB
XP_346132.5
195 aa
PLA2G12B,  G.gallus
phospholipase A2, group XIIB
XP_004942085.1
201 aa
pla2g12b,  X.tropicalis
phospholipase A2, group XIIB
NP_001007917.1
196 aa
pla2g12b,  D.rerio
phospholipase A2, group XIIB
NP_998595.2
231 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes.
Mavoungou E, et al. J Acquir Immune Defic Syndr Hum Retrovirol 16, 1-9 (1997).
Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death.
Schröder HC, et al. Neurotoxicology 19, 683-8 (1998).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PLA2G12 (pfam06951)
  Group XII secretory phospholipase A2 precursor (PLA2G12).
PLA2G12 (pfam06951)
  Group XII secretory phospholipase A2 precursor (PLA2G12).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pla2g12b includes H.sapiens PLA2G12B and R.norvegicus Pla2g12b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (12 transcripts, 9 species)
Mammalia - mammals (8 transcripts, 7 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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