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HomoloGene:1000. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CLDN4,  H.sapiens
claudin 4
NP_001296.1
209 aa
CLDN4,  P.troglodytes
claudin 4
XP_001148188.1
209 aa
CLDN4,  M.mulatta
claudin 4
XP_001112477.1
209 aa
CLDN4,  C.lupus
claudin 4
XP_005621019.1
210 aa
CLDN4,  B.taurus
claudin 4
NP_001014413.1
209 aa
Cldn4,  M.musculus
claudin 4
NP_034033.1
210 aa
Cldn4,  R.norvegicus
claudin 4
NP_001012022.1
210 aa
CLDN4,  G.gallus
claudin 4
XP_003642430.1
209 aa
cldnb,  D.rerio
claudin b
NP_571838.1
215 aa
cldna,  D.rerio
claudin a
NP_571837.2
206 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Clinicopathological significance of claudin-4 in gastric carcinoma.
Zhu JL, et al. World J Surg Oncol 11, 150 (2013).
Value of claudin-4 immunostaining in the diagnosis of mesothelioma.
Ordóñez NG. Am J Clin Pathol 139, 611-9 (2013).
Claudins play a role in normal and tumor cell motility.
Webb PG, et al. BMC Cell Biol 14, 19 (2013).
Claudin-4 as therapeutic target in cancer.
Neesse A, et al. Arch Biochem Biophys 524, 64-70 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PMP22_Claudin (cl15797)
  PMP-22/EMP/MP20/Claudin family.
PMP22_Claudin (cl17758)
  PMP-22/EMP/MP20/Claudin family.
Claudin_2 (cl17758)
  PMP-22/EMP/MP20/Claudin tight junction.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cldn4 includes H.sapiens CLDN4 and R.norvegicus Cldn4.

 

 

 

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