GTR Home > Tests > Onco microarray for CLL

Overview

Test name

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Onco microarray for CLL

Purpose of the test

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This is a clinical test intended for Help: Diagnosis, Prognostic, Recurrence, Risk Assessment

Condition

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8 conditions tested. Click Indication tab for more information.

Methodology

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Molecular Genetics
DDeletion/duplication analysis
Microarray
  • Agilent SureSelect
HDetection of homozygosity
Microarray
  • Agilent SureSelect

Summary of what is tested

16 genes and variants, 7 chromosomal regions. Click Methodology tab for more information.

Genes

  • Gene: AKT1 (14q32.33)
  • Gene: ALK (2p23.2-23.1)
  • Gene: ATM (11q22.3)
  • Gene: BCL10 (1p22.3)
  • Gene: BCL11A (2p16.1)
  • Gene: BCL2 (18q21.33)
  • Gene: BCL3 (19q13.32)
  • Gene: BCL6 (3q27.3)
  • Gene: CCND1 (11q13.3)
  • Gene: FGF2 (4q28.1)
  • Gene: IGH (14q32.33)
  • Gene: ITK (5q33.3)
  • Gene: MYB (6q23.3)
  • Gene: MYBL1 (8q13.1)
  • Gene: MYC (8q24.21)
  • Gene: TP53 (17p13.1)

Chromosomal regions/Mitochondria

  • 11q22.3 (ATM)
  • 12p13
  • 13q14.3
  • Chromosomal gains, losses, deletions, and markers
  • homozygosity detection
  • partial trisomy 12
  • trisomy 12

Clinical validity

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Not provided

Clinical utility

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Establish or confirm diagnosis

Citations

Guidance for management

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Testing strategy

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Copy number analysis by aCGH to identyfy alterations in genes involved in lymphoid differentiation, proliferation, cell cycle and to provide important diagnostic and prognostic information that is routinely used in risk stratification for treatment.

How to order

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For more information, please contact the laboratory directly.

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