GTR Home > Tests > Dyslipidemias / Early atherosclerosis


Test name


Dyslipidemias / Early atherosclerosis

Purpose of the test


This is a clinical test intended for Help: Diagnosis, Mutation Confirmation, Pre-symptomatic, Predictive, Prognostic



1 condition tested. Click Indication tab for more information.


Molecular Genetics
CSequence analysis of the entire coding region
Next-Generation (NGS)/Massively parallel sequencing (MPS)
  • Qiagen QIAcube

Summary of what is tested

84 genes and variants. Click Methodology tab for more information.


Clinical validity


Not provided

Clinical utility


Establish or confirm diagnosis

Guidance for management

Predictive risk information for patient and/or family members

How to order


Order URL Help:

Test services

  • Clinical Testing/Confirmation of Mutations Identified Previously
  • Confirmation of research findings
  • Custom Deletion/Duplication Testing
  • Custom Sequence Analysis
  • Data Storage and Backup

Practice guidelines

  • ACMG, 2016
    Recommendations for reporting of secondary findings in clinical exome and genome sequencing, 2016 update (ACMG SF v2.0): a policy statement of the American College of Medical Genetics and Genomics.
  • ACMG, 2015
    ACMG policy statement: updated recommendations regarding analysis and reporting of secondary findings in clinical genome-scale sequencing.
  • Feldman et al., 2015
    Recommendations for the management of patients with familial hypercholesterolemia.
  • EAS, 2014
    Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society.
  • PLEF, 2014
    Management of familial hypercholesterolemia in children and adolescents. Position paper of the Polish Lipid Expert Forum.
  • Int'l FH Foundation, 2014
    Integrated guidance on the care of familial hypercholesterolaemia from the International FH Foundation.
  • ACMG, 2013
    ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.
  • PLEF, 2013
    Management of familial heterozygous hypercholesterolemia: Position Paper of the Polish Lipid Expert Forum.
  • NHFA, 2012
    INTERIM guidelines for the diagnosis and management of familial hypercholesterolaemia.
  • NLAEP, 2011
    Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia.
  • NICE, 2008
    Identification and management of familial hypercholesterolaemia
  • IPMFH, 2004
    Guidelines for the diagnosis and management of heterozygous familial hypercholesterolemia.

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