GTR Home > Tests > Alzheimer: Apo-E, PSEN1, PSEN2, A2M and APP genes sequence analysis (select exons)

Overview

Test order codeHelp: G-1012-01

Test name

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Alzheimer: Apo-E, PSEN1, PSEN2, A2M and APP genes sequence analysis (select exons)

Purpose of the test

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This is a clinical test intended for Help: Diagnosis

Condition

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4 conditions tested. Click Indication tab for more information.

Methodology

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Molecular Genetics
CSequence analysis of the entire coding region
Bi-directional Sanger Sequence Analysis

Summary of what is tested

5 genes and variants. Click Methodology tab for more information.

Genes

Clinical validity

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Not provided

Clinical utility

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Not provided

How to order

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Not provided

Practice guidelines

  • CCCDTD, 2014
    Fourth Canadian Consensus Conference on the Diagnosis and Treatment of Dementia: recommendations for family physicians.
  • ACMG/NSGC, 2011
    Genetic counseling and testing for Alzheimer disease: joint practice guidelines of the American College of Medical Genetics and the National Society of Genetic Counselors.
  • EFNS, 2010
    EFNS guidelines for the diagnosis and management of Alzheimer's disease.
  • AHRQ, 2010
    Preventing Alzheimer's disease and cognitive decline.

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