GTR Home > Tests > UGT1A1 Gene Polymorphism (TA Repeat)


Test order codeHelp: 7064

Test name


UGT1A1 Gene Polymorphism (TA Repeat)

Purpose of the test


This is a clinical test intended for Help: Diagnosis, Monitoring, Mutation Confirmation, Pre-symptomatic, Risk Assessment, Screening



1 condition tested. Click Indication tab for more information.


Molecular Genetics
TTargeted variant analysis
Bi-directional Sanger Sequence Analysis
  • Applied Biosystems 310 capillary sequencing instrument

Summary of what is tested

1 genes and variants. Click Methodology tab for more information.


Clinical validity


Not provided

Clinical utility


Guidance for selecting a drug therapy and/or dose

  • UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity. - PubMed ID: 11990381

How to order


Specimen type: Whole blood with anticoagulant EDTA (3-6mL). Send blood samples at room temperature. blood samples can be preserved at 2-8°C before shipping, but for no longer than one week. Do not freeze the blood. DNA sample: 3 ug of DNA(100-250 ng/µL) in TE, AE or sterile water. Send DNA samples at room temperature. To avoid sample loss and contamination, please use 2.0mL screw cap tubes, or wrap de caps of each microtube with parafilm. The A260/280 ratio should be 1.8-2.0. SNa sample should run on an agarose gel as a single band, showing no degradation, alongside with a quantitative DNA marker.
Order URL Help:

Test services

  • Clinical Testing/Confirmation of Mutations Identified Previously, Order code: 7064

Clinical resources

Practice guidelines

  • NACB, 2010
    National Academy of Clinical Biochemistry, Clinical practice considerations. In: Laboratory medicine practice guidelines: guidelines and recommendations for laboratory analysis and application of pharmacogenetics to clinical practice, 2010

Consumer resources

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