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KALRN kalirin RhoGEF kinase

Gene ID: 8997, updated on 17-Oct-2021
Gene type: protein coding
Also known as: DUO; CHD5; DUET; TRAD; CHDS5; HAPIP; ARHGEF24

Summary

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus.
GeneReviews: Not available
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
GeneReviews: Not available
Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.
GeneReviews: Not available
New gene functions in megakaryopoiesis and platelet formation.
GeneReviews: Not available

Genomic context

Location:
3q21.1-q21.2
Sequence:
Chromosome: 3; NC_000003.12 (124033341..124726325)
Total number of exons:
66

Links

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