GTR Home > Genes

PRKRA protein activator of interferon induced protein kinase EIF2AK2

Also known as: RAX; PACT; DYT16; HSD14


This gene encodes a protein kinase activated by double-stranded RNA which mediates the effects of interferon in response to viral infection. Mutations in this gene have been associated with dystonia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]

Associated conditions

See all available tests in GTR for this gene

Dystonia 16
MedGen: C2677567OMIM: 612067GeneReviews: Not available
See labs

Genomic context

Chromosome: 2; NC_000002.12 (178431414..178451240, complement)
Total number of exons:


IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.

Support Center