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GFM1 G elongation factor mitochondrial 1

Also known as: EFG; GFM; EFG1; EFGM; EGF1; hEFG1; COXPD1

Summary

Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008]

Associated conditions

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DescriptionTests
Combined oxidative phosphorylation deficiency 1
MedGen: C1836797OMIM: 609060GeneReviews: Not available
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Genomic context

Location:
3q25.32
Sequence:
Chromosome: 3; NC_000003.12 (158644497..158692572)
Total number of exons:
19

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