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CAMP cathelicidin antimicrobial peptide

Gene ID: 820, updated on 8-Oct-2018
Also known as: LL37; CAP18; CRAMP; HSD26; CAP-18; FALL39; FALL-39

Summary

This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014]

Genomic context

Location:
3p21.31
Sequence:
Chromosome: 3; NC_000003.12 (48223347..48225491)
Total number of exons:
4

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