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TAF15 TATA-box binding protein associated factor 15

Gene ID: 8148, updated on 16-Sep-2018
Also known as: Npl3; RBP56; TAF2N; TAFII68


This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]

Associated conditions

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Epithelial-myoepithelial carcinoma
MedGen: C1275278OMIM: 612237GeneReviews: Not available
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Genomic context

Chromosome: 17; NC_000017.11 (35809455..35847242)
Total number of exons:


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