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PALB2 partner and localizer of BRCA2

Gene ID: 79728, updated on 6-May-2023
Gene type: protein coding
Also known as: FANCN; PNCA3


This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. [provided by RefSeq, Jul 2008]

Associated conditions

See all available tests in GTR for this gene

Familial cancer of breastSee labs
Fanconi anemia complementation group NSee labs
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
GeneReviews: Not available
Hereditary cancer-predisposing syndrome
MedGen: C0027672GeneReviews: Not available
See labs
Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
GeneReviews: Not available
Pancreatic cancer, susceptibility to, 3
MedGen: C3150547OMIM: 613348GeneReviews: Not available
See labs
Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
GeneReviews: Not available

Genomic context

Chromosome: 16; NC_000016.10 (23603165..23641310, complement)
Total number of exons:


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