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XPA XPA, DNA damage recognition and repair factor

Also known as: XP1; XPAC

Summary

This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]

Genomic context

Location:
9q22.3
Sequence:
Chromosome: 9; NC_000009.12 (97654398..97697409, complement)
Total number of exons:
10

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