SLC18A2 solute carrier family 18 member A2
Gene ID: 6571, updated on 17-Sep-2024Gene type: protein coding
Also known as: SVAT; SVMT; VAT2; VMAT2; PKDYS2
- See all available tests in GTR for this gene
- Go to complete Gene record for SLC18A2
- Go to Variation Viewer for SLC18A2 variants
Summary
This gene encodes an transmembrane protein that functions as an ATP-dependent transporter of monoamines, such as dopamine, norepinephrine, serotonin, and histamine. This protein transports amine neurotransmitters into synaptic vesicles. Polymorphisms in this gene may be associated with schizophrenia, bipolar disorder, and other neurological/psychiatric ailments. [provided by RefSeq, Jun 2018]
Associated conditions
See all available tests in GTR for this gene
| Description | Tests |
|---|---|
| Brain dopamine-serotonin vesicular transport disease | See labs |
Genomic context
- Location:
- 10q25.3
- Sequence:
- Chromosome: 10; NC_000010.11 (117241114..117279430)
- Total number of exons:
- 16
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for SLC18A2 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- Variation ViewerRelated Variants
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