ZNF674 zinc finger protein 674

Gene ID: 641339, updated on 11-Apr-2024
Gene type: protein coding
Also known as: MRX92; ZNF673B

Summary

This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disabilities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]

Copy number response

Description
Copy number response Triplosensitivity No evidence available (Last evaluated 2023-03-28) ClinGen Genome Curation Page Haploinsufficency No evidence available (Last evaluated 2023-03-28) ClinGen Genome Curation PagePubMed

Genomic context

Location:: Xp11.3

Sequence:: Chromosome: X; NC_000023.11 (46497725..46545421, complement)

Total number of exons:: 6

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Variation

Resource	Links for this gene
ClinVar	Variants reported to ClinVar
dbVar	Studies and variants
SNP	Variation Viewer for ZNF674 variants
Genome viewer	Explore NCBI-annotated and select non-NCBI annotated genome assemblies

Links

ClinVar
Related medical variations
dbVar
Link from Gene to dbVar
OMIM
Link to related OMIM entry
PubMed (OMIM)
Gene links to PubMed derived from omim_pubmed_cited links
RefSeq RNAs
Link to Nucleotide RefSeq RNAs
RefSeqGene
Link to Nucleotide RefSeqGenes
Variation Viewer
Related Variants
ZNF674 database

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