ADCY10 adenylate cyclase 10
Gene ID: 55811, updated on 5-Mar-2024Gene type: protein coding
Also known as: SAC; HCA2; SACI; Sacy; hsAC; HEL-S-7a
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Summary
The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014]
Associated conditions
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Description | Tests |
---|---|
Familial idiopathic hypercalciuria | See labs |
Genomic context
- Location:
- 1q24.2
- Sequence:
- Chromosome: 1; NC_000001.11 (167809386..167914134, complement)
- Total number of exons:
- 36
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | Variation Viewer for ADCY10 variants |
Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ADCY10 database
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- MedGenRelated information in MedGen
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- Variation ViewerRelated Variants
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