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XAF1 XIAP associated factor 1

Gene ID: 54739, updated on 6-Sep-2021
Gene type: protein coding
Also known as: BIRC4BP; XIAPAF1; HSXIAPAF1


This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

Genomic context

Chromosome: 17; NC_000017.11 (6755408..6775647)
Total number of exons:


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