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PDGFRL platelet derived growth factor receptor like

Also known as: PDGRL; PRLTS

Summary

This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
Hepatocellular carcinoma
MedGen: C2239176OMIM: 114550GeneReviews: Not available
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Genomic context

Location:
8p22
Sequence:
Chromosome: 8; NC_000008.11 (17576433..17643133)
Total number of exons:
7

Links

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