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OAS3 2'-5'-oligoadenylate synthetase 3

Gene ID: 4940, updated on 22-Aug-2021
Gene type: protein coding
Also known as: p100; p100OAS

Summary

This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance. [provided by RefSeq, Jul 2008]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
Genome-wide association studies identify genetic loci related to alcohol consumption in Korean men.
GeneReviews: Not available
Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.
GeneReviews: Not available
Preliminary evidence of genetic determinants of adiponectin response to fenofibrate in the Genetics of Lipid Lowering Drugs and Diet Network.
GeneReviews: Not available

Genomic context

Location:
12q24.13
Sequence:
Chromosome: 12; NC_000012.12 (112938463..112973251)
Total number of exons:
16

Links

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