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ITGA1 integrin subunit alpha 1

Gene ID: 3672, updated on 7-Oct-2018
Also known as: VLA1; CD49a

Summary

This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]

Genomic context

Location:
5q11.2
Sequence:
Chromosome: 5; NC_000005.10 (52788302..52953655)
Total number of exons:
29

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