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QRFP pyroglutamylated RFamide peptide

Gene ID: 347148, updated on 8-Jul-2021
Gene type: protein coding
Also known as: P518; 26RFa

Summary

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. The encoded products are members of the RFamide family of neuropeptides, characterized by their common protein C-terminus consisting of an arginine (R) and an amidated phenylalanine (F). These products include the neuropeptides 26RFa and the N-terminally extended form, 43RFa. Both of these neuropeptides bind to the pyroglutamylated RFamide peptide receptor (QRFPR) and may regulate blood pressure, reproduction and food intake in rodents. [provided by RefSeq, Jul 2015]

Genomic context

Location:
9q34.12
Sequence:
Chromosome: 9; NC_000009.12 (130892707..130896812, complement)
Total number of exons:
3

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