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IAPP islet amyloid polypeptide

Gene ID: 3375, updated on 19-Sep-2021
Gene type: protein coding
Also known as: DAP; IAP

Summary

This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity. [provided by RefSeq, Jul 2016]

Genomic context

Location:
12p12.1
Sequence:
Chromosome: 12; NC_000012.12 (21354959..21379980)
Total number of exons:
4

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