RPA4 replication protein A4
Gene ID: 29935, updated on 23-Mar-2024Gene type: protein coding
Also known as: HSU24186
- See all available tests in GTR for this gene
- Go to complete Gene record for RPA4
- Go to Variation Viewer for RPA4 variants
Summary
This gene encodes a single-stranded DNA-binding protein that is the 30-kDa subunit of the replication protein A complex. Replication protein A is an essential factor for DNA double-strand break repair and cell cycle checkpoint activation. The encoded protein localizes to DNA repair foci and may be involved in the cellular DNA damage response. This protein may also play a role in inhibiting viral replication.[provided by RefSeq, Apr 2010]
Genomic context
- Location:
- Xq21.33
- Sequence:
- Chromosome: X; NC_000023.11 (96883908..96885467)
- Total number of exons:
- 1
Variation
| Resource | Links for this gene |
|---|---|
| ClinVar | Variants reported to ClinVar |
| dbVar | Studies and variants |
| SNP | Variation Viewer for RPA4 variants |
| Genome viewer | Explore NCBI-annotated and select non-NCBI annotated genome assemblies |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- RefSeqGeneLink to Nucleotide RefSeqGenes
- RPA4 @ LOVD
- Variation ViewerRelated Variants
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