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H19 H19, imprinted maternally expressed transcript (non-protein coding)

Also known as: ASM; BWS; WT2; ASM1; D11S813E; LINC00008; NCRNA00008


This gene is located in an imprinted region of chromosome 11 near the insulin-like growth factor 2 (IGF2) gene. This gene is only expressed from the maternally-inherited chromosome, whereas IGF2 is only expressed from the paternally-inherited chromosome. The product of this gene is a long non-coding RNA which functions as a tumor suppressor. Mutations in this gene have been associated with Beckwith-Wiedemann Syndrome and Wilms tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Copy number response

Copy number response

No evidence available (Last evaluated (2012-03-22)

ClinGen Genome Curation Page

No evidence available (Last evaluated (2012-03-22)

ClinGen Genome Curation Page

Genomic context

Chromosome: 11; NC_000011.10 (1995176..2001466, complement)
Total number of exons:


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