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QPCT glutaminyl-peptide cyclotransferase

Gene ID: 25797, updated on 6-Sep-2021
Gene type: protein coding
Also known as: QC; GCT; sQC

Summary

This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
GeneReviews: Not available
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
GeneReviews: Not available
Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.
GeneReviews: Not available

Genomic context

Location:
2p22.2
Sequence:
Chromosome: 2; NC_000002.12 (37344630..37373322)
Total number of exons:
7

Links

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