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QPCT glutaminyl-peptide cyclotransferase

Gene ID: 25797, updated on 6-Sep-2021
Gene type: protein coding
Also known as: QC; GCT; sQC


This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]

Associated conditions

See all available tests in GTR for this gene

A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia.
GeneReviews: Not available
Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
GeneReviews: Not available
Investigation of single nucleotide polymorphisms and biological pathways associated with response to TNFα inhibitors in patients with rheumatoid arthritis.
GeneReviews: Not available

Genomic context

Chromosome: 2; NC_000002.12 (37344630..37373322)
Total number of exons:


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