IKZF2 IKAROS family zinc finger 2
Gene ID: 22807, updated on 5-Mar-2024Gene type: protein coding
Also known as: ANF1A2; HELIOS; ZNF1A2; ZNFN1A2
- See all available tests in GTR for this gene
- Go to complete Gene record for IKZF2
- Go to Variation Viewer for IKZF2 variants
Summary
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
Associated conditions
See all available tests in GTR for this gene
Description | Tests |
---|---|
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. GeneReviews: Not available |
Genomic context
- Location:
- 2q34
- Sequence:
- Chromosome: 2; NC_000002.12 (212999698..213152456, complement)
- Total number of exons:
- 11
Variation
Resource | Links for this gene |
---|---|
ClinVar | Variants reported to ClinVar |
dbVar | Studies and variants |
SNP | GeneView ReportGo to Variation Viewer for IKZF2 variants |
1000 Genomes | See 1000 Genomes Browser (GRCh37.p13) |
- ClinVarRelated medical variations
- dbVarLink from Gene to dbVar
- OMIMLink to related OMIM entry
- PubMed (OMIM)Gene links to PubMed derived from omim_pubmed_cited links
- RefSeq RNAsLink to Nucleotide RefSeq RNAs
- SNP: GeneViewSNPs linked from GeneView
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