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ACSL1 acyl-CoA synthetase long chain family member 1

Gene ID: 2180, updated on 15-Apr-2019
Also known as: ACS1; LACS; FACL1; FACL2; LACS1; LACS2

Summary

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Genomic context

Location:
4q35.1
Sequence:
Chromosome: 4; NC_000004.12 (184755595..184826593, complement)
Total number of exons:
28

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