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ABCA3 ATP binding cassette subfamily A member 3

Also known as: ABC3; ABC-C; SMDP3; LBM180; EST111653


The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The full transporter encoded by this gene may be involved in development of resistance to xenobiotics and engulfment during programmed cell death. [provided by RefSeq, Jul 2008]

Associated conditions

See all available tests in GTR for this gene

Surfactant metabolism dysfunction, pulmonary, 3
MedGen: C1970456OMIM: 610921GeneReviews: Not available
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Genomic context

Chromosome: 16; NC_000016.10 (2275878..2340746, complement)
Total number of exons:


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