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DRD5 dopamine receptor D5

Also known as: DBDR; DRD1B; DRD1L2

Summary

This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
Attention deficit hyperactivity disorder
MedGen: C1263846OMIM: 143465GeneReviews: Not available
See labs
Blepharospasm
MedGen: C2930898OMIM: 606798GeneReviews: Not available
See labs

Copy number response

Description
Copy number response
Haploinsufficency

No evidence available (Last evaluated (2012-05-15)

ClinGen Genome Curation Page
Triplosensitivity

No evidence available (Last evaluated (2012-05-15)

ClinGen Genome Curation Page

Genomic context

Location:
4p16.1
Sequence:
Chromosome: 4; NC_000004.12 (9781634..9784009)
Total number of exons:
1

Links

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