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DAB1 DAB adaptor protein 1

Gene ID: 1600, updated on 25-Nov-2021
Gene type: protein coding
Also known as: SCA37

Summary

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.
GeneReviews: Not available
A genome-wide association meta-analysis of plasma Aβ peptides concentrations in the elderly.
GeneReviews: Not available
Common genetic variation and the control of HIV-1 in humans.
GeneReviews: Not available
Genetic variants associated with disordered eating.
GeneReviews: Not available
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
GeneReviews: Not available
Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients.
GeneReviews: Not available
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
GeneReviews: Not available
Genome-wide survival analysis of age at onset of alcohol dependence in extended high-risk COGA families.
GeneReviews: Not available
Spinocerebellar ataxia 37See labs

Genomic context

Location:
1p32.2-p32.1
Sequence:
Chromosome: 1; NC_000001.11 (56994778..58546726, complement)
Total number of exons:
27

Links

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