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CHRNB1 cholinergic receptor nicotinic beta 1 subunit

Gene ID: 1140, updated on 9-Aug-2021
Gene type: protein coding
Also known as: ACHRB; CHRNB; CMS1D; CMS2A; CMS2C; SCCMS

Summary

The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome. [provided by RefSeq, Jul 2008]

Genomic context

Location:
17p13.1
Sequence:
Chromosome: 17; NC_000017.11 (7445061..7457710)
Total number of exons:
11

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