GTR Home > Genes

L3HYPDH trans-L-3-hydroxyproline dehydratase

Gene ID: 112849, updated on 11-Jun-2021
Gene type: protein coding
Also known as: C14orf149

Summary

The protein encoded by this gene is a dehydratase that converts trans-3-hydroxy-L-proline to delta(1)-pyrroline-2-carboxylate. This enzyme may function to degrade dietary proteins that contain trans-3-hydroxy-L-proline as well as other proteins such as collagen IV. The encoded protein can be converted to an epimerase by changing a threonine to a cysteine at a catalytic site. [provided by RefSeq, Sep 2016]

Genomic context

Location:
14q23.1
Sequence:
Chromosome: 14; NC_000014.9 (59472606..59505266, complement)
Total number of exons:
7

Links

IMPORTANT NOTE: NIH does not independently verify information submitted to the GTR; it relies on submitters to provide information that is accurate and not misleading. NIH makes no endorsements of tests or laboratories listed in the GTR. GTR is not a substitute for medical advice. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional.

Support Center