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ABCA7 ATP binding cassette subfamily A member 7

Gene ID: 10347, updated on 22-Jan-2020
Also known as: AD9; ABCX; ABCA-SSN

Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008]

Associated conditions

See all available tests in GTR for this gene

DescriptionTests
Alzheimer disease, type 9
MedGen: C4282179OMIM: 608907GeneReviews: Not available
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Genomic context

Location:
19p13.3
Sequence:
Chromosome: 19; NC_000019.10 (1040107..1065572)
Total number of exons:
47

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