GTR Home > Conditions/Phenotypes > Age-related macular degeneration 13

Summary

Age-related macular degeneration (ARMD) is a multifactorial disorder of the central retina that is the most prevalent cause of progressive vision loss in the developed world. As in other chronic age-related diseases, most cases result from interplay between multiple environmental and genetic factors, with a resultant spectrum of phenotypes. In rare cases, ARMD may manifest early, but there is an exponential rise in prevalence after the age of 60 years (summary by Pras et al., 2015). For a phenotypic description and a discussion of genetic heterogeneity of age-related macular degeneration (ARMD), see 603075. [from OMIM]

Available tests

17 tests are in the database for this condition.

Genes See tests for all associated and related genes

  • Also known as: AHUS3, ARMD13, C3BINA, C3b-INA, FI, IF, KAF, CFI
    Summary: complement factor I

Clinical features

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