GTR Home > Conditions/Phenotypes > 15q13.3 microdeletion syndrome

Summary

Excerpted from the GeneReview: 15q13.3 Microdeletion
Individuals with the 15q13.3 microdeletion are at increased risk for a wide range of clinical manifestations including intellectual disability, seizures, autism spectrum disorders, and schizophrenia; however, the microdeletion itself does not appear to lead to a clinically recognizable syndrome and a subset of persons with the deletion have no obvious clinical findings. Behavioral problems are common and mainly comprise poor attention span, hyperactivity, mood disorder, and aggressive and/or impulsive behavior. Intellectual disability, observed in about half of the individuals with this recurrent deletion, is usually mild but can be moderate to severe.

Available tests

10 tests are in the database for this condition.

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Genes See tests for all associated and related genes

  • Also known as: CHRNA7-2, NACHRA7, CHRNA7
    Summary: cholinergic receptor nicotinic alpha 7 subunit

  • Also known as: BTEB3, FKLF2, NSLP1, RFLAT-1, RFLAT1, KLF13
    Summary: Kruppel like factor 13

Clinical features

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