GTR Home > Conditions/Phenotypes > Charcot-Marie-Tooth disease and deafness

Summary

Excerpted from the GeneReview: Charcot-Marie-Tooth Neuropathy Type 1
Charcot-Marie-Tooth neuropathy type 1 (CMT1) is a demyelinating peripheral neuropathy characterized by distal muscle weakness and atrophy, sensory loss, and slow nerve conduction velocity. It is usually slowly progressive and often associated with pes cavus foot deformity and bilateral foot drop. Affected individuals usually become symptomatic between age five and 25 years. Fewer than 5% of individuals become wheelchair dependent. Life span is not shortened.

Available tests

71 tests are in the database for this condition.

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Associated genes

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