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Cenani-Lenz syndactyly syndrome

Synonyms
Cenani syndactylism; SYNDACTYLY, TYPE VII; Syndactyly Cenani Lenz type; Syndactyly type 7
Modes of inheritance
Autosomal recessive inheritance (Orphanet)

Summary

Cenani-Lenz syndactyly syndrome (CLSS) is an autosomal recessive disorder characterized by mainly by anomalies of distal limb development, with fusion and disorganization of metacarpal and phalangeal bones, radius and ulnar shortening, radioulnar synostosis, and severe syndactyly of hands and feet. Mild facial dysmorphism is present in most patients. Kidney anomalies, including renal agenesis and hypoplasia, occur in over half of patients (summary by Li et al., 2010). [from OMIM]

Available tests

27 tests are in the database for this condition.

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Clinical tests (27 available)

Molecular Genetics Tests

Genes See tests for all associated and related genes

  • Also known as: CLSS, CMS17, LRP-4, LRP10, MEGF7, SOST2, LRP4
    Summary: LDL receptor related protein 4

Clinical features

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Imported from Human Phenotype Ontology (HPO)

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