GTR Home > Conditions/Phenotypes > IRAK4 deficiency


IRAK4 deficiency is an autosomal recessive primary immunodeficiency that impairs Toll (see TLR4; 603030)/IL1R (see IL1R1; 147810) immunity, except for the TLR3 (603029)- and TLR4-interferon-alpha (IFNA; 147660)/beta (IFNB; 147640) pathways (Ku et al., 2007). [from OMIM]

Available tests

10 tests are in the database for this condition.

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Genes See tests for all associated and related genes

  • Also known as: IPD1, IRAK-4, NY-REN-64, REN64, IRAK4
    Summary: interleukin 1 receptor associated kinase 4

Clinical features


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