GTR Home > Conditions/Phenotypes > Craniosynostosis 4

Summary

Craniosynostosis is a primary abnormality of skull growth involving premature fusion of the cranial sutures such that the growth velocity of the skull often cannot match that of the developing brain. This produces skull deformity and, in some cases, raises intracranial pressure, which must be treated promptly to avoid permanent neurodevelopmental disability (summary by Fitzpatrick, 2013). Craniosynostosis-4 includes lambdoid, sagittal, metopic, coronal, and multisuture forms. For a discussion of genetic heterogeneity of craniosynostosis, see CRS1 (123100). [from GTR]

Available tests

10 tests are in the database for this condition.

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Genes See tests for all associated and related genes

  • Also known as: CHYTS, CRS4, PE-2, PE2, ERF
    Summary: ETS2 repressor factor

Clinical features

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