GTR Home > Conditions/Phenotypes > Obesity


Obesity means having too much body fat. It is different from being overweight, which means weighing too much. The weight may come from muscle, bone, fat, and/or body water. Both terms mean that a person's weight is greater than what's considered healthy for his or her height. . Obesity occurs over time when you eat more calories than you use. The balance between calories-in and calories-out differs for each person. Factors that might affect your weight include your genetic makeup, overeating, eating high-fat foods, and not being physically active. . Being obese increases your risk of diabetes, heart disease, stroke, arthritis, and some cancers. If you are obese, losing even 5 to 10 percent of your weight can delay or prevent some of these diseases. For example, that means losing 10 to 20 pounds if you weigh 200 pounds. NIH: National Institute of Diabetes and Digestive and Kidney Diseases. [from MedlinePlus]

Available tests

149 tests are in the database for this condition.

Check Related conditions for additional relevant tests.

Genes See tests for all associated and related genes

  • Also known as: ADRB2R, ADRBR, B2AR, BAR, BETA2AR, ADRB2
    Summary: adrenoceptor beta 2

  • Also known as: BETA3AR, ADRB3
    Summary: adrenoceptor beta 3

  • Also known as: AGRT, ART, ASIP2, AGRP
    Summary: agouti related neuropeptide

  • Also known as: CART, CARTPT
    Summary: CART prepropeptide

  • Also known as: ARHR2, COLED, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1, ENPP1
    Summary: ectonucleotide pyrophosphatase/phosphodiesterase 1

  • Also known as: MTLRP, GHRL
    Summary: ghrelin and obestatin prepropeptide

  • Also known as: , MC4R
    Summary: melanocortin 4 receptor

  • Also known as: SHP, SHP1, NR0B2
    Summary: nuclear receptor subfamily 0 group B member 2

  • Also known as: ACTH, CLIP, LPH, MSH, NPP, POC, POMC
    Summary: proopiomelanocortin

  • Also known as: CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma, PPARG
    Summary: peroxisome proliferator activated receptor gamma

  • Also known as: ERRL1, PERC, PGC-1(beta), PGC1B, PPARGC1B
    Summary: PPARG coactivator 1 beta

  • Also known as: SDCN, SYND3, SDC3
    Summary: syndecan 3

  • Also known as: bHLHe14, SIM1
    Summary: single-minded family bHLH transcription factor 1

  • Also known as: SLC25A7, UCP, UCP1
    Summary: uncoupling protein 1

  • Also known as: SLC25A9, UCP3
    Summary: uncoupling protein 3

Clinical features


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