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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_012061.1Â RefSeqGene
- Range
-
5001..64886
- Download
- GenBank, FASTA, Sequence Viewer (Graphics), LRG_491
mRNA and Protein(s)
-
NM_001042355.2 → NP_001035814.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
See identical proteins and their annotated locations for NP_001035814.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks one exon in the 5' UTR and a second in-frame exon in the coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Variants 2 and 3 encode the same isoform.
- Source sequence(s)
-
AJ250014, AK056226, AL050166, BI458962, BX642061, DA157717, DA785459, DA940312
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Related
- ENSP00000457576.1, ENST00000569418.5
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001042412.3 → NP_001035877.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
See identical proteins and their annotated locations for NP_001035877.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3) has an alternate 5' terminal exon, and lacks one exon in the 5' UTR and another in-frame exon in the coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Variants 2 and 3 encode the same isoform.
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Related
- ENSP00000381574.2, ENST00000398568.6
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378743.1 → NP_001365672.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 1
Status: REVIEWED
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS45482.1
- UniProtKB/Swiss-Prot
- O94934, Q7L3N6, Q96EH0, Q9NQC7, Q9NZX9
- UniProtKB/TrEMBL
-
A8KAB0
- Related
- ENSP00000392025.3, ENST00000427738.8
- Conserved Domains (3) summary
-
- smart01052
Location:472 → 540
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:593 → 948
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:307 → 471
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378744.1 → NP_001365673.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
Status: REVIEWED
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Related
- ENSP00000454515.1, ENST00000564326.5
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378745.1 → NP_001365674.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
Status: REVIEWED
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378746.1 → NP_001365675.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
Status: REVIEWED
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378747.1 → NP_001365676.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
Status: REVIEWED
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378748.1 → NP_001365677.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
Status: REVIEWED
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378749.1 → NP_001365678.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
Status: REVIEWED
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378750.1 → NP_001365679.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 2
Status: REVIEWED
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS42164.1
- UniProtKB/TrEMBL
-
A8KAB0
- Conserved Domains (3) summary
-
- smart01052
Location:469 → 537
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:590 → 945
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 468
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378751.1 → NP_001365680.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC007728
- UniProtKB/TrEMBL
-
A8KAB0
- Conserved Domains (3) summary
-
- smart01052
Location:459 → 527
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:580 → 935
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 458
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378752.1 → NP_001365681.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC007728
- UniProtKB/TrEMBL
-
A8KAB0
- Conserved Domains (3) summary
-
- smart01052
Location:459 → 527
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:580 → 935
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 458
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378753.1 → NP_001365682.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 3
Status: REVIEWED
- Source sequence(s)
-
AC007728
- UniProtKB/TrEMBL
-
A8KAB0
- Related
- ENSP00000456488.2, ENST00000568704.2
- Conserved Domains (3) summary
-
- smart01052
Location:459 → 527
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:580 → 935
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:304 → 458
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378754.1 → NP_001365683.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC007728
- UniProtKB/TrEMBL
-
B3KND1
- Conserved Domains (3) summary
-
- smart01052
Location:247 → 315
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:368 → 723
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:82 → 246
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_001378755.1 → NP_001365684.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 4
Status: REVIEWED
- Source sequence(s)
-
AC007728
- UniProtKB/TrEMBL
-
B3KND1
- Conserved Domains (3) summary
-
- smart01052
Location:247 → 315
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:368 → 723
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:82 → 246
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
-
NM_015247.3 → NP_056062.1  ubiquitin carboxyl-terminal hydrolase CYLD isoform 1
See identical proteins and their annotated locations for NP_056062.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
- Source sequence(s)
-
AC007728
- Consensus CDS
-
CCDS45482.1
- UniProtKB/Swiss-Prot
- O94934, Q7L3N6, Q96EH0, Q9NQC7, Q9NZX9
- UniProtKB/TrEMBL
-
A8KAB0
- Related
- ENSP00000308928.9, ENST00000311559.13
- Conserved Domains (3) summary
-
- smart01052
Location:472 → 540
- CAP_GLY; Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network
- cd02670
Location:593 → 948
- Peptidase_C19N; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
- pfam16607
Location:307 → 471
- CYLD_phos_site; Phosphorylation region of CYLD, unstructured
RNA
-
NR_166071.1 RNA Sequence
Status: REVIEWED
- Source sequence(s)
-
AC007728