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    ECM7 Ecm7p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851164, updated on 13-Apr-2024

    Summary

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    Gene symbol
    ECM7
    Gene description
    Ecm7p
    Primary source
    SGD:S000004435
    Locus tag
    YLR443W
    See related
    AllianceGenome:SGD:S000004435
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    ZRG15
    Summary
    Involved in calcium ion transport. Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See ECM7 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (1022625..1023971)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene ribosomal 40S subunit protein S1A Neighboring gene chromatin-silencing protein SIR3 Neighboring gene Gmc2p Neighboring gene hexokinase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic analysis of the regulation of the voltage-gated calcium channel homolog Cch1 by the γ subunit homolog Ecm7 and cortical ER protein Scs2 in yeast. Kato T, et al. PLoS One, 2017. PMID 28742147, Free PMC Article
    2. Identification and characterization of upstream open reading frames (uORF) in the 5' untranslated regions (UTR) of genes in Saccharomyces cerevisiae. Zhang Z, et al. Curr Genet, 2005 Aug. PMID 16012843
    3. Hypotonic stress-induced calcium signaling in Saccharomyces cerevisiae involves TRP-like transporters on the endoplasmic reticulum membrane. Rigamonti M, et al. Cell Calcium, 2015 Feb. PMID 25573187
    4. Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. Kim H, et al. J Biol Chem, 2003 Mar 21. PMID 12524434
    5. Zinc-regulated genes in Saccharomyces cerevisiae revealed by transposon tagging. Yuan DS. Genetics, 2000 Sep. PMID 10978274, Free PMC Article

    See all (33) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in calcium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cell wall organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in fungal-type cell wall organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell cortex of cell tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Ecm7p
    NP_013548.1
    • Putative integral membrane protein with a role in calcium uptake; non-essential protein; mutant has cell wall defects and Ca+ uptake deficiencies; transcription is induced under conditions of zinc deficiency

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      1022625..1023971
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182331.1 → NP_013548.1  TPA: Ecm7p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013548.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VZ78, Q06200, Q2VQX1
      UniProtKB/TrEMBL
      A0A6A5PTX5, C7GSL2, C8ZE51, N1NYW2
      Conserved Domains (1) summary
      cl24030
      Location:96 → 308
      SUR7; SUR7/PalI family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q06200.1

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