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    KCNMA1 potassium calcium-activated channel subfamily M alpha 1 [ Gallus gallus (chicken) ]

    Gene ID: 374065, updated on 3-Apr-2024

    Summary

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    Symbol
    KCNMA1provided by CGNC
    Full Name
    potassium calcium-activated channel subfamily M alpha 1provided by CGNC
    Primary source
    CGNC:49029
    See related
    Ensembl:ENSGALG00010022174
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    slo; cSlo; slo1; KCNMA; KCa1.1
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: 6
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (14141872..14585542)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (14128187..14571478)

    Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112532710 Neighboring gene discs large MAGUK scaffold protein 5 Neighboring gene leucine rich melanocyte differentiation associated Neighboring gene uncharacterized LOC107053653 Neighboring gene uncharacterized LOC124418046

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Palmitoylation of STREX domain confers cerebroside sensitivity to the BKCa channel. Zhang Y, et al. Biochim Biophys Acta, 2014 Oct. PMID 24946143
    2. Expression of BK-type calcium-activated potassium channel splice variants during chick cochlear development. Kim JM, et al. J Comp Neurol, 2010 Jul 1. PMID 20503427, Free PMC Article
    3. Highly specific alternative splicing of transcripts encoding BK channels in the chicken's cochlea is a minor determinant of the tonotopic gradient. Miranda-Rottmann S, et al. Mol Cell Biol, 2010 Jul. PMID 20479127, Free PMC Article
    4. Effects of axial stretch on sarcolemmal BKCa channels in post-hatch chick ventricular myocytes. Iribe G, et al. Exp Physiol, 2010 Jun. PMID 20176677
    5. Characterization of a newly found stretch-activated KCa,ATP channel in cultured chick ventricular myocytes. Kawakubo T, et al. Am J Physiol, 1999 Jun. PMID 10362660

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. findings suggest that palmitoylation of the STREX domain is necessary for cerebrosides to activate the BKCa channel
      Title: Palmitoylation of STREX domain confers cerebroside sensitivity to the BKCa channel.
    2. These studies identify for the first time a central role for beta-catenin in mediating Slo surface expression.
      Title: Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression.
    3. This comparative systems approach suggests conservation in BK function across different species in addition to novel functions that may include the initiation of signals relevant to cell death/survival.
      Title: Conserved BK channel-protein interactions reveal signals relevant to cell death and survival.
    4. Currents from the alpha (Slo)-subunit of hair- cell BK channel alone do not show dramatic increases in response to changes in divalent calcium ion (Ca2+) concentrations at -50 millivolts expressed in low-frequency hair cells.
      Title: β4-subunit increases Slo responsiveness to physiological Ca2+ concentrations and together with β1 reduces surface expression of Slo in hair cells.
    5. These results indicate that delays in protein synthesis and trafficking/scaffolding of channel subunits underlie the late acquisition of BK currents in cochlear hair cells.
      Title: Expression of BK-type calcium-activated potassium channel splice variants during chick cochlear development.
    6. The present results suggest that axial stretch activates BK(Ca) channels via a stretch-induced increase in the cytosolic Na(+) concentration followed by an increased Ca(2+) influx.
      Title: Effects of axial stretch on sarcolemmal BKCa channels in post-hatch chick ventricular myocytes.
    7. By analyzing the complete sequences of cSlo cDNAs from the cochlea, we show that most transcripts lack alternative exons. Transcripts with more than one alternative exon constitute only 10% of the total.
      Title: Highly specific alternative splicing of transcripts encoding BK channels in the chicken's cochlea is a minor determinant of the tonotopic gradient.
    8. MAGI-1 interacts with Slo1 channel proteins and suppresses Slo1 expression on the cell surface.
      Title: MAGI-1 interacts with Slo1 channel proteins and suppresses Slo1 expression on the cell surface.
    9. Tamoxifen inhibits BK channels in chick cochlea without alterations in voltage-dependent activation.
      Title: Tamoxifen inhibits BK channels in chick cochlea without alterations in voltage-dependent activation.
    10. These results suggest that SAK(CA) senses membrane tension through an interaction between STREX and submembranous components.
      Title: Stress-Axis Regulated Exon (STREX) in the C terminus of BK(Ca) channels is responsible for the stretch sensitivity.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables large conductance calcium-activated potassium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in potassium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    calcium-activated potassium channel subunit alpha-1
    Names
    BK channel
    BKCA alpha
    calcium-activated potassium channel, subfamily M subunit alpha-1
    k(VCA)alpha
    maxi K channel
    maxiK
    potassium large conductance calcium-activated channel, subfamily M, alpha member 1
    slo homolog
    slo-alpha
    slowpoke homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204224.2 → NP_989555.2  calcium-activated potassium channel subunit alpha-1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000231
      UniProtKB/Swiss-Prot
      O12942, O13110, O93569, Q8AYS8, Q98951, Q9PS76
      Related
      ENSGALP00010032525.1, ENSGALT00010053992.1
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:516 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:424 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      14141872..14585542
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040702202.2 → XP_040558136.1  calcium-activated potassium channel subunit alpha-1 isoform X7

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:153 → 329
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:279 → 439
      PRK10537; voltage-gated potassium channel protein

    2. XM_046942681.1 → XP_046798637.1  calcium-activated potassium channel subunit alpha-1 isoform X7

    3. XM_040702201.2 → XP_040558135.1  calcium-activated potassium channel subunit alpha-1 isoform X7

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:153 → 329
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:279 → 439
      PRK10537; voltage-gated potassium channel protein

    4. XM_015288158.4 → XP_015143644.1  calcium-activated potassium channel subunit alpha-1 isoform X16

      UniProtKB/TrEMBL
      D3X742

    5. XM_025151438.3 → XP_025007206.1  calcium-activated potassium channel subunit alpha-1 isoform X35

      UniProtKB/TrEMBL
      A0A8V0ZM63
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:516 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:424 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    6. XM_015288167.3 → XP_015143653.1  calcium-activated potassium channel subunit alpha-1 isoform X24

      UniProtKB/TrEMBL
      D3X742
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    7. XM_015288168.4 → XP_015143654.1  calcium-activated potassium channel subunit alpha-1 isoform X25

      UniProtKB/TrEMBL
      D3X737
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    8. XM_015288149.4 → XP_015143635.1  calcium-activated potassium channel subunit alpha-1 isoform X6

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    9. XM_040702206.2 → XP_040558140.1  calcium-activated potassium channel subunit alpha-1 isoform X11

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    10. XM_040702207.2 → XP_040558141.1  calcium-activated potassium channel subunit alpha-1 isoform X12

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    11. XM_015288165.4 → XP_015143651.1  calcium-activated potassium channel subunit alpha-1 isoform X22

      UniProtKB/TrEMBL
      D3X748
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    12. XM_015288166.4 → XP_015143652.1  calcium-activated potassium channel subunit alpha-1 isoform X23

      UniProtKB/TrEMBL
      D3X751
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    13. XM_040702203.2 → XP_040558137.1  calcium-activated potassium channel subunit alpha-1 isoform X8

      UniProtKB/TrEMBL
      D3X737
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    14. XM_040702196.2 → XP_040558130.1  calcium-activated potassium channel subunit alpha-1 isoform X1

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    15. XM_040702197.2 → XP_040558131.1  calcium-activated potassium channel subunit alpha-1 isoform X2

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    16. XM_040702204.2 → XP_040558138.1  calcium-activated potassium channel subunit alpha-1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0ZNX7
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 393
      PRK10537; voltage-gated potassium channel protein

    17. XM_040702205.2 → XP_040558139.1  calcium-activated potassium channel subunit alpha-1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0ZNX7
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 393
      PRK10537; voltage-gated potassium channel protein

    18. XM_040702199.2 → XP_040558133.1  calcium-activated potassium channel subunit alpha-1 isoform X4

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    19. XM_040702200.2 → XP_040558134.1  calcium-activated potassium channel subunit alpha-1 isoform X5

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    20. XM_040702208.2 → XP_040558142.1  calcium-activated potassium channel subunit alpha-1 isoform X14

      UniProtKB/TrEMBL
      A0A8V0ZNX7
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 393
      PRK10537; voltage-gated potassium channel protein

    21. XM_040702209.2 → XP_040558143.1  calcium-activated potassium channel subunit alpha-1 isoform X15

      UniProtKB/TrEMBL
      A0A8V0ZNX7
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 393
      PRK10537; voltage-gated potassium channel protein

    22. XM_015288159.4 → XP_015143645.1  calcium-activated potassium channel subunit alpha-1 isoform X17

      UniProtKB/TrEMBL
      D3X737
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    23. XM_015288181.4 → XP_015143667.1  calcium-activated potassium channel subunit alpha-1 isoform X37

      UniProtKB/TrEMBL
      A0A8V0ZM63
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    24. XM_025151440.3 → XP_025007208.1  calcium-activated potassium channel subunit alpha-1 isoform X39

      UniProtKB/TrEMBL
      A0A8V0ZM63
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:516 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:424 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    25. XM_046942680.1 → XP_046798636.1  calcium-activated potassium channel subunit alpha-1 isoform X29

    26. XM_015288173.3 → XP_015143659.1  calcium-activated potassium channel subunit alpha-1 isoform X31

      UniProtKB/TrEMBL
      D3X737
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    27. XM_015288184.4 → XP_015143670.1  calcium-activated potassium channel subunit alpha-1 isoform X41

      UniProtKB/TrEMBL
      A0A8V0ZM88, D3X747
      Related
      ENSGALP00010032550.1, ENSGALT00010054019.1
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    28. XM_015288185.3 → XP_015143671.1  calcium-activated potassium channel subunit alpha-1 isoform X43

      UniProtKB/TrEMBL
      D3X747
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    29. XM_015288160.4 → XP_015143646.1  calcium-activated potassium channel subunit alpha-1 isoform X18

      UniProtKB/TrEMBL
      D3X738
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    30. XM_015288161.4 → XP_015143647.1  calcium-activated potassium channel subunit alpha-1 isoform X19

      UniProtKB/TrEMBL
      D3X738
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    31. XM_015288183.4 → XP_015143669.1  calcium-activated potassium channel subunit alpha-1 isoform X40

      UniProtKB/TrEMBL
      A0A8V0ZM63
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    32. XM_015288174.4 → XP_015143660.1  calcium-activated potassium channel subunit alpha-1 isoform X30

      UniProtKB/TrEMBL
      D3X738
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    33. XM_015288176.3 → XP_015143662.1  calcium-activated potassium channel subunit alpha-1 isoform X32

      UniProtKB/TrEMBL
      A0A8V0ZUL3, D3X738
      Related
      ENSGALP00010032534.1, ENSGALT00010054003.1
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    34. XM_025151443.3 → XP_025007211.1  calcium-activated potassium channel subunit alpha-1 isoform X44

      UniProtKB/TrEMBL
      D3X750
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:516 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:424 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    35. XM_040702211.2 → XP_040558145.1  calcium-activated potassium channel subunit alpha-1 isoform X47

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    36. XM_015288154.3 → XP_015143640.1  calcium-activated potassium channel subunit alpha-1 isoform X13

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    37. XM_015288171.4 → XP_015143657.1  calcium-activated potassium channel subunit alpha-1 isoform X27

      UniProtKB/TrEMBL
      D3X748
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    38. XM_015288172.4 → XP_015143658.1  calcium-activated potassium channel subunit alpha-1 isoform X28

      UniProtKB/TrEMBL
      D3X751
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    39. XM_040702198.2 → XP_040558132.1  calcium-activated potassium channel subunit alpha-1 isoform X3

      UniProtKB/TrEMBL
      D3X739
      Conserved Domains (2) summary
      PLN03192
      Location:195 → 371
      PLN03192; Voltage-dependent potassium channel; Provisional
      PRK10537
      Location:321 → 481
      PRK10537; voltage-gated potassium channel protein

    40. XM_015288162.4 → XP_015143648.1  calcium-activated potassium channel subunit alpha-1 isoform X20

      UniProtKB/TrEMBL
      D3X734
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    41. XM_015288163.4 → XP_015143649.1  calcium-activated potassium channel subunit alpha-1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0ZNZ2, D3X734
      Related
      ENSGALP00010032532.1, ENSGALT00010054001.1
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    42. XM_015288178.4 → XP_015143664.1  calcium-activated potassium channel subunit alpha-1 isoform X33

      UniProtKB/TrEMBL
      D3X734
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    43. XM_015288179.3 → XP_015143665.1  calcium-activated potassium channel subunit alpha-1 isoform X34

      UniProtKB/TrEMBL
      D3X734
      Conserved Domains (4) summary
      pfam00520
      Location:188 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      pfam07885
      Location:284 → 369
      Ion_trans_2; Ion channel
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    44. XM_015288187.4 → XP_015143673.1  calcium-activated potassium channel subunit alpha-1 isoform X45

      UniProtKB/Swiss-Prot
      O12942, O13110, O93569, Q8AYS8, Q98951, Q9PS76
      UniProtKB/TrEMBL
      A0A8V0ZGW8
      Related
      ENSGALP00010032558.1, ENSGALT00010054027.1
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    45. XM_015288189.4 → XP_015143675.1  calcium-activated potassium channel subunit alpha-1 isoform X46

      UniProtKB/Swiss-Prot
      O12942, O13110, O93569, Q8AYS8, Q98951, Q9PS76
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    46. XM_025151439.3 → XP_025007207.1  calcium-activated potassium channel subunit alpha-1 isoform X36

      UniProtKB/TrEMBL
      A0A8V0ZM63
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:516 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:424 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    47. XM_015288182.4 → XP_015143668.1  calcium-activated potassium channel subunit alpha-1 isoform X38

      UniProtKB/TrEMBL
      A0A8V0ZM63
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    48. XM_025151442.3 → XP_025007210.1  calcium-activated potassium channel subunit alpha-1 isoform X42

      UniProtKB/TrEMBL
      D3X750
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:516 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:424 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    49. XM_015288170.4 → XP_015143656.1  calcium-activated potassium channel subunit alpha-1 isoform X26

      UniProtKB/TrEMBL
      D3X751
      Conserved Domains (3) summary
      pfam00520
      Location:157 → 374
      Ion_trans; Ion transport protein
      pfam03493
      Location:523 → 611
      BK_channel_a; Calcium-activated BK potassium channel alpha subunit
      cl21454
      Location:388 → 501
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      14128187..14571478
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046919735.1 → XP_046775691.1  calcium-activated potassium channel subunit alpha-1 isoform X7

    2. XM_046919776.1 → XP_046775732.1  calcium-activated potassium channel subunit alpha-1 isoform X7

    3. XM_046919777.1 → XP_046775733.1  calcium-activated potassium channel subunit alpha-1 isoform X7

    4. XM_046919745.1 → XP_046775701.1  calcium-activated potassium channel subunit alpha-1 isoform X16

    5. XM_046919764.1 → XP_046775720.1  calcium-activated potassium channel subunit alpha-1 isoform X35

    6. XM_046919753.1 → XP_046775709.1  calcium-activated potassium channel subunit alpha-1 isoform X24

    7. XM_046919754.1 → XP_046775710.1  calcium-activated potassium channel subunit alpha-1 isoform X25

    8. XM_046919734.1 → XP_046775690.1  calcium-activated potassium channel subunit alpha-1 isoform X6

    9. XM_046919739.1 → XP_046775695.1  calcium-activated potassium channel subunit alpha-1 isoform X11

    10. XM_046919740.1 → XP_046775696.1  calcium-activated potassium channel subunit alpha-1 isoform X12

    11. XM_046919751.1 → XP_046775707.1  calcium-activated potassium channel subunit alpha-1 isoform X22

    12. XM_046919752.1 → XP_046775708.1  calcium-activated potassium channel subunit alpha-1 isoform X23

    13. XM_046919736.1 → XP_046775692.1  calcium-activated potassium channel subunit alpha-1 isoform X8

    14. XM_046919728.1 → XP_046775684.1  calcium-activated potassium channel subunit alpha-1 isoform X1

    15. XM_046919729.1 → XP_046775685.1  calcium-activated potassium channel subunit alpha-1 isoform X2

    16. XM_046919737.1 → XP_046775693.1  calcium-activated potassium channel subunit alpha-1 isoform X9

    17. XM_046919738.1 → XP_046775694.1  calcium-activated potassium channel subunit alpha-1 isoform X10

    18. XM_046919731.1 → XP_046775687.1  calcium-activated potassium channel subunit alpha-1 isoform X4

    19. XM_046919732.1 → XP_046775688.1  calcium-activated potassium channel subunit alpha-1 isoform X5

    20. XM_046919742.1 → XP_046775698.1  calcium-activated potassium channel subunit alpha-1 isoform X14

    21. XM_046919743.1 → XP_046775699.1  calcium-activated potassium channel subunit alpha-1 isoform X15

    22. XM_046919746.1 → XP_046775702.1  calcium-activated potassium channel subunit alpha-1 isoform X17

    23. XM_046919766.1 → XP_046775722.1  calcium-activated potassium channel subunit alpha-1 isoform X37

    24. XM_046919768.1 → XP_046775724.1  calcium-activated potassium channel subunit alpha-1 isoform X39

    25. XM_046919758.1 → XP_046775714.1  calcium-activated potassium channel subunit alpha-1 isoform X29

    26. XM_046919760.1 → XP_046775716.1  calcium-activated potassium channel subunit alpha-1 isoform X31

    27. XM_046919770.1 → XP_046775726.1  calcium-activated potassium channel subunit alpha-1 isoform X41

      UniProtKB/TrEMBL
      A0A8V0ZM88

    28. XM_046919772.1 → XP_046775728.1  calcium-activated potassium channel subunit alpha-1 isoform X43

    29. XM_046919747.1 → XP_046775703.1  calcium-activated potassium channel subunit alpha-1 isoform X18

    30. XM_046919748.1 → XP_046775704.1  calcium-activated potassium channel subunit alpha-1 isoform X19

    31. XM_046919769.1 → XP_046775725.1  calcium-activated potassium channel subunit alpha-1 isoform X40

    32. XM_046919759.1 → XP_046775715.1  calcium-activated potassium channel subunit alpha-1 isoform X30

    33. XM_046919761.1 → XP_046775717.1  calcium-activated potassium channel subunit alpha-1 isoform X32

      UniProtKB/TrEMBL
      A0A8V0ZUL3

    34. XM_046919773.1 → XP_046775729.1  calcium-activated potassium channel subunit alpha-1 isoform X44

    35. XM_046919778.1 → XP_046775734.1  calcium-activated potassium channel subunit alpha-1 isoform X47

    36. XM_046919741.1 → XP_046775697.1  calcium-activated potassium channel subunit alpha-1 isoform X13

    37. XM_046919756.1 → XP_046775712.1  calcium-activated potassium channel subunit alpha-1 isoform X27

    38. XM_046919757.1 → XP_046775713.1  calcium-activated potassium channel subunit alpha-1 isoform X28

    39. XM_046919730.1 → XP_046775686.1  calcium-activated potassium channel subunit alpha-1 isoform X3

    40. XM_046919749.1 → XP_046775705.1  calcium-activated potassium channel subunit alpha-1 isoform X20

    41. XM_046919750.1 → XP_046775706.1  calcium-activated potassium channel subunit alpha-1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0ZNZ2

    42. XM_046919762.1 → XP_046775718.1  calcium-activated potassium channel subunit alpha-1 isoform X33

    43. XM_046919763.1 → XP_046775719.1  calcium-activated potassium channel subunit alpha-1 isoform X34

    44. XM_046919774.1 → XP_046775730.1  calcium-activated potassium channel subunit alpha-1 isoform X45

      UniProtKB/TrEMBL
      A0A8V0ZGW8

    45. XM_046919775.1 → XP_046775731.1  calcium-activated potassium channel subunit alpha-1 isoform X46

    46. XM_046919765.1 → XP_046775721.1  calcium-activated potassium channel subunit alpha-1 isoform X36

    47. XM_046919767.1 → XP_046775723.1  calcium-activated potassium channel subunit alpha-1 isoform X38

    48. XM_046919771.1 → XP_046775727.1  calcium-activated potassium channel subunit alpha-1 isoform X42

    49. XM_046919755.1 → XP_046775711.1  calcium-activated potassium channel subunit alpha-1 isoform X26

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8AYS8.2 GenPept UniProtKB/Swiss-Prot:Q8AYS8

    Gene LinkOut

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