|
| Status |
Public on Sep 07, 2019 |
| Title |
WT-derived T-ALL 120 (RNA-Seq) |
| Sample type |
SRA |
| |
|
| Source name |
spleen
|
| Organism |
Mus musculus |
| Characteristics |
strain: BALB/c
genotype: Rag2-/-Il2rg-/-
tissue: spleen
disease state: tumor
donor thymus genotype: Wild type
|
| Extracted molecule |
total RNA |
| Extraction protocol |
Total RNA was extracted
Total RNA was converted to mRNA libraries using KAPA Stranded mRNA-Seq kits from KAPA Biosystems following the manufacturer’s protocols
|
| |
|
| Library strategy |
RNA-Seq |
| Library source |
transcriptomic |
| Library selection |
cDNA |
| Instrument model |
Illumina HiSeq 2500 |
| |
|
| Data processing |
RNA-Seq reads were mapped to the mouse mm10 reference genome guided by UCSC gene models by OSA aligner implemented in ArrayStudio software from Qiagen
Genome_build: mm10
Supplementary_files_format_and_content: gene expression matrix in txt format
|
| |
|
| Submission date |
Sep 06, 2019 |
| Last update date |
Sep 10, 2019 |
| Contact name |
Qi Zhao |
| E-mail(s) |
qi.zhao@regeneron.com
|
| Organization name |
Regeneron Pharmaceuticals Inc
|
| Street address |
777 Old Saw Mill River Road
|
| City |
Tarrytown |
| ZIP/Postal code |
10591 |
| Country |
USA |
| |
|
| Platform ID |
GPL17021 |
| Series (2) |
| GSE137057 |
Gene expression profile of thymus transplantation based spontaneous murine T cell acute lymphoblastic leukemia (T-ALL) model |
| GSE137181 |
Therapeutic targeting of Notch signaling and immune checkpoint blockade in a spontaneous, genetically-heterogeneous mouse model of T-cell acute lymphoblastic leukemia |
|
| Relations |
| BioSample |
SAMN12710629 |
| SRA |
SRX6815682 |
