|
| Status |
Public on May 02, 2019 |
| Title |
Subject 104004 at Week 0,non-lesional |
| Sample type |
RNA |
| |
|
| Source name |
homo sapiens skin biopsy, Week 0, non-lesional
|
| Organism |
Homo sapiens |
| Characteristics |
Sex: F
time: Week0
tissue: NL
treatment: Placebo
subject id: 104004
race: BLACK OR AFRICAN AMERICAN
ethnicity: NOT HISPANIC OR LATINO
easi: 38.5
scorad: 57.8
|
| Treatment protocol |
Atopic dermatitis patients randomized 1:1 to dupilumab 200mg or placebo weekly for 16 weeks, with lesional and non-lesional biopsies taken at baseline, week 4 (only lesional) and week 16 both lesional and non lesional
|
| Growth protocol |
n/a
|
| Extracted molecule |
total RNA |
| Extraction protocol |
RNA was extracted according to manufacturer's instructions.
|
| Label |
biotin
|
| Label protocol |
n/a
|
| |
|
| Hybridization protocol |
RNA was hybridized to Affymetrix Human U133Plus 2.0 gene arrays
|
| Scan protocol |
n/a
|
| Description |
gene expression data from lesional and non-lesional skin phenotypes of patients with moderate-to-severe atopic dermatitis
|
| Data processing |
Expression measures were obtained by using the GC Robust Multi-array Average algorithm.
|
| |
|
| Submission date |
May 01, 2019 |
| Last update date |
Oct 01, 2019 |
| Contact name |
Mayte Suarez-Farinas |
| E-mail(s) |
mayte.suarezfarinas@mssm.edu
|
| Organization name |
Mount SinaiSchool of Medicine
|
| Street address |
1425 Madison Ave, L2-70C, Box 1077,
|
| City |
New York |
| State/province |
NY |
| ZIP/Postal code |
10075 |
| Country |
USA |
| |
|
| Platform ID |
GPL570 |
| Series (1) |
| GSE130588 |
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis |
|
