|
Status |
Public on Jun 01, 2014 |
Title |
7668610127_R05C02 (batch2) |
Sample type |
genomic |
|
|
Source name |
7668610127_R05C02
|
Organism |
Homo sapiens |
Characteristics |
diagnosis: Control gender: FEMALE race: White age: 78 tau_a1: H1 tau_a2: H1 batch: 2 tissue: Peripheral Blood
|
Extracted molecule |
genomic DNA |
Extraction protocol |
genomic DNA was extracted and purified with standard methods
|
Label |
Cy5 and Cy3
|
Label protocol |
Standard Illumina Protocol
|
|
|
Hybridization protocol |
bisulphite converted DNA was amplified, fragmented and hybridised to Illumina Infinium Human Methylation450 Beadchip using standard Illumina protocol
|
Scan protocol |
Arrays were imaged using BeadArray Reader using standard recommended Illumina scanner setting
|
Data processing |
BeadStudio software Raw data was processed using the Illumina GenomeStudio software (version 2010.3). Background correction and color normalization were performed using the R package minfi version 1.2.0 and normalization using Subset-quantile Within Array Normalization (SWAN). Probes were excluded from further analysis if >95% samples had detection p-value >0.01. Raw data (Unmethylated and methylated signal intensities) linked as supplementary files on Series record.
|
|
|
Submission date |
Jan 02, 2014 |
Last update date |
Jun 01, 2014 |
Contact name |
Giovanni Coppola |
E-mail(s) |
gcoppola@ucla.edu
|
Phone |
310-794-4172
|
Organization name |
UCLA
|
Department |
Psychiatry and Neurology
|
Lab |
Neurogenetics
|
Street address |
1524 Gonda, 695 Charles Young Drive South
|
City |
Los Angeles |
State/province |
CA |
ZIP/Postal code |
90095 |
Country |
USA |
|
|
Platform ID |
GPL13534 |
Series (1) |
GSE53740 |
An Epigenetic Signature in Peripheral Blood Associated with Neurodegenerative Tauopathy and the Risk-Associated Haplotype on 17q21.31 |
|