NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE99670 Query DataSets for GSE99670
Status Public on Dec 19, 2017
Title Metabolic products of an obesity-associated microbiome impact host metabolism and disease risk by altering the epigenome
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Genome binding/occupancy profiling by high throughput sequencing
Summary We profiled the gut microbiome and chromatin features at DNA cis-regulatory elements in colon epithelium from mice fed either an obesogenic or control diet.
 
Overall design Examination of 2 different histone modifications and gene expression in mice colon epithelium, microbiome in male fecal samples
 
Contributor(s) Qin Y, Roberts JD, Grimm SA, Lih FB, Deterding LJ, Li R, Chrysovergis K, Wade PA
Citation(s) 29361968
Submission date Jun 05, 2017
Last update date Jul 25, 2021
Contact name Paul A Wade
E-mail(s) wadep2@niehs.nih.gov
Phone 919-541-3392
Organization name NIEHS
Department Laboratory of Molecular Carcinogenesis
Street address 111 TW Alexander Drive
City Research Triangle Park
State/province NC
ZIP/Postal code 27709
Country USA
 
Platforms (2)
GPL13112 Illumina HiSeq 2000 (Mus musculus)
GPL19057 Illumina NextSeq 500 (Mus musculus)
Samples (84)
GSM2649537 HFD_male_H3K4me1_ChIPSeq_replicate1
GSM2649538 HFD_male_H3K4me1_ChIPSeq_replicate2
GSM2649539 HFD_male_H3K4me1_ChIPSeq_replicate3
Relations
BioProject PRJNA389277
SRA SRP108605

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE99670_RAW.tar 17.7 Gb (http)(custom) TAR (of BED, BIGWIG)
GSE99670_RNAseq_gene_counts_per_sample.txt.gz 852.4 Kb (ftp)(http) TXT
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap