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| Status |
Public on Nov 03, 2017 |
| Title |
Common lymphoid progenitor derivation of plasmacytoid dendritic cells is mediated by Bcl11a |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Plasmacytoid dendritic cells (pDC) specialize in type I interferon production to coordinate innate and adaptive immunity. We identify two pDC subsets in vivo, evaluate their genome-wide expression, and demonstrate a developmental requirement for Bcl11a to provide insight into this enigmatic cell type.
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| Overall design |
ChIP sequenicng was performed for a transcription factor of BCL11A in the Nalm6 B cell line and the Raji B cell line. Input was sequenced and used as a control.
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| |
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| Contributor(s) |
Dekker J, Tucker H, Iyer V |
| Citation(s) |
29038163 |
| |
| Submission date |
May 17, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Bum-Kyu Lee |
| E-mail(s) |
bklee92@gmail.com
|
| Phone |
512-232-8046
|
| Organization name |
University of Texas at Austin
|
| Street address |
2506 Speedway Stop A5000
|
| City |
Austin |
| State/province |
TX |
| ZIP/Postal code |
78712 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (4)
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| Relations |
| BioProject |
PRJNA387006 |
| SRA |
SRP107199 |
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