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Series GSE99019 Query DataSets for GSE99019
Status Public on Nov 03, 2017
Title Common lymphoid progenitor derivation of plasmacytoid dendritic cells is mediated by Bcl11a  
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary Plasmacytoid dendritic cells (pDC) specialize in type I interferon production to coordinate innate and adaptive immunity. We identify two pDC subsets in vivo, evaluate their genome-wide expression, and demonstrate a developmental requirement for Bcl11a to provide insight into this enigmatic cell type.
 
Overall design ChIP sequenicng was performed for a transcription factor of BCL11A in the Nalm6 B cell line and the Raji B cell line. Input was sequenced and used as a control.
 
Contributor(s) Dekker J, Tucker H, Iyer V
Citation(s) 29038163
Submission date May 17, 2017
Last update date May 15, 2019
Contact name Bum-Kyu Lee
E-mail(s) bklee92@gmail.com
Phone 512-232-8046
Organization name University of Texas at Austin
Street address 2506 Speedway Stop A5000
City Austin
State/province TX
ZIP/Postal code 78712
Country USA
 
Platforms (1)
GPL11154 Illumina HiSeq 2000 (Homo sapiens)
Samples (4)
GSM2630343 Nalm6_BCL11A_ChIPSeq
GSM2630344 Raji_BCL11A_ChIPSeq
GSM2630345 Nalm6_Input
Relations
BioProject PRJNA387006
SRA SRP107199

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE99019_RAW.tar 320.0 Kb (http)(custom) TAR (of TXT)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data provided as supplementary file

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