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| Status |
Public on May 08, 2020 |
| Title |
Autoimunne arthritis-associated B cell methylome in mice with proteoglycan (PG)-induced arthritis (PGIA) [methylation] |
| Organism |
Mus musculus |
| Experiment type |
Methylation profiling by genome tiling array
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| Summary |
Autoimmune arthritis was induced by three consecutive PG injections. B cells were affinity purified from mice and methylated DNA fractions were enriched by methylated-CpG island recovery assay (MIRA) method and investigated on microarray platforms.
Several hundred differentially methylated regions were detected in the investigated B cell epigenomes
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| |
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| Overall design |
Four control (non-arthritic) and four arthritic B cell samples were analyzed on NimbleGen's DNA Methylation 385K CpG Island Plus RefSeq Promoter Array
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| Contributor(s) |
Rauch TA, Glant TT |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
May 15, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Tibor T Glant |
| E-mail(s) |
Tibor_Glant@rush.edu
|
| Organization name |
Rush University Medical Center
|
| Department |
Orthopedic Surgery
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| Lab |
Molecular Medicine
|
| Street address |
1735 West Harrison
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| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60612 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL18360 |
NimbleGen Mouse DNA Methylation 385K CpG Island Plus RefSeq Promoter Array [2007-02-27_MM8_CpG_Island_Pro] |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA386873 |
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