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GEO help: Mouse over screen elements for information. |
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Status |
Public on May 05, 2019 |
Title |
Chemerin inhibits cancer progression by impairing the maturation of neovessels |
Organism |
Mus musculus |
Experiment type |
Expression profiling by high throughput sequencing
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Summary |
Chemerin is a leukocyte chemoattractant and an adipokine. Overexpression of chemerin by tumor cells or the host inhibits tumor progression in different mouse models, through a mechanism involving the chemerin receptor CMKLR1 and impairment of endothelial cell/pericyte interactions in neovessels.
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Overall design |
mRNA profiles of LLC tumors (5 days following graft in the back of syngeneic C57BL/6 mice) expressing or not chemerin were generated, in duplicate, using Illumina Hiseq1500.
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Contributor(s) |
Dubois-Vedrenne I, Robert V, De Henau O, Al Delbany D, Vernimmen M, Vosters O, Langa-Vives F, Libert F, Luangsay S, Wittamer V, Parmentier M |
Citation(s) |
34548907 |
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Submission date |
May 08, 2017 |
Last update date |
Sep 29, 2021 |
Contact name |
Frederick Libert |
E-mail(s) |
flibert@ulb.ac.be
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Organization name |
ULB
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Department |
IRIBHM
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Lab |
C2-140
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Street address |
808 route de Lennik
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City |
Brussels |
ZIP/Postal code |
B-1070 |
Country |
Belgium |
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Platforms (1) |
GPL18480 |
Illumina HiSeq 1500 (Mus musculus) |
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Samples (4)
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Relations |
BioProject |
PRJNA385853 |
SRA |
SRP106653 |
Supplementary file |
Size |
Download |
File type/resource |
GSE98672_RPM_of_LLC_cells_expressing_or_not_chemerin.txt.gz |
575.9 Kb |
(ftp)(http) |
TXT |
SRA Run Selector |
Raw data are available in SRA |
Processed data are available on Series record |
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